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Hydroxyurea or Hydroxycarbamide

Muby Chemicals established in the year 1976, is pioneer in Manufacturing Chemicals for Oil and Gas Exploration, Hydraulic Fracturing (Fracking) and coiled tube Chemicals.Our advanced chemistry leading to an innovative and high-performance product range is coupled with effective on and off site management services.

We are manufacturer of Specialty chemicals, Pharmaceutical Excipients, Fragrance & Flavorchemicals in India, which are of IP, BP, USP, Ph. Eur., FCC or Food Grade, ACS, AR or Analytical Reagent Grade, LR or Laboratory Reagent Grade, Pure and Technical Grades of various chemicals.

Category:
Description

Hydroxycarbamide, also known as hydroxyurea, is a medication used in sickle-cell disease, chronic myelogenous leukemia, cervical cancer, and polycythemia vera.

Hydroxycarbamide BP Grade
Ph Eur

DEFINITION
N-Hydroxyurea
Content: 97.5 per cent to 102.0 per cent (anhydrous substance).

CHARACTERS
Appearance: White or almost white, crystalline powder, hygroscopic.
Solubility: Freely soluble in water, practically insoluble in alcohol. It shows polymorphism.

IDENTIFICATION
A. Infrared absorption spectrophotometry.
B. Examine the chromatograms obtained in the test for urea.

TESTS
Urea: Thin-layer chromatography.
Chlorides: Maximum 50 ppm.
Heavy metals: Maximum 10 ppm.
Water:  Maximum 0.5 per cent, determined on 2.00 g.
Sulfated ash: Maximum 0.1 per cent, determined on 1.0 g.

Hydroxyurea USP Grade
CH4N2O2 76.05
Urea, hydroxy-.
Hydroxyurea [127-07-1].
Hydroxyurea contains not less than 97.0 percent and not more than 103.0 percent of CH4N2O2, calculated on the dried basis.

Identification: Infrared Absorption 197K.
Loss on drying: Dry it in vacuum at 60 for 3 hours: it loses not more than 1.0% of its weight.
Residue on ignition: not more than 0.50%.
Heavy metals: not more than 0.003%.
Urea and related compounds: To pass the test.

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